Thielavin A

• UNSPSC Description:

  Thielavin A is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin A specifically inhibits the conversion of arachidonic acid into prostaglandin H2. Thielavin A has no anti-inflammatory activity on intravenous injection or on oral administration[1].

• Target Antigen:

  Prostaglandin Receptor

• Type:

  Natural Products

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology; Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/thielavin-a.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC1=C(C)C(C)=C(C(O)=O)C(O)=C1C)C2=C(C)C(C)=C(OC(C3=C(C)C=C(O)C(C)=C3O)=O)C(C)=C2O

• Molecular Weight:

  538.54

• References & Citations:

  [1]Kitahara N, et al. Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricola. J Antibiot (Tokyo). 1981;34(12):1562-1568.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  71950-66-8