Biotin-EDA

• Description:

  Biotin-EDA is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/biotin-eda.html

• Purity:

  98.0

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C (NCCN) CCCC[C@@H]1SC[C@] ([C@]1 ([H]) N2) ([H]) NC2=O

• Molecular Formula:

  C12H22N4O2S

• Molecular Weight:

  286.39

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Alkyl-Chain Linkers

• CAS Number:

  111790-37-5