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Mecbotamab vedotin

CAT: 0804-HY-145622-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-145622-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mecbotamab vedotin (BA3011) is a pH dependent antibody drug conjugate (ADC) targeting AXL. Mecbotamab vedotin can significantly inhibit AXL in DU145 cells and LCLC-103H cells and kills cells. Mecbotamab vedotin can be used for research on cancer such as lung cancer, pancreatic cancer and prostate cancer. The antibody component is Mecbotamab , and the ADC toxin molecule is Vedotin (HY-15162).
CAS Number
2460400-64-8
Product Name Alternative
BA3011; CAB-Axl-ADC; CAB-anti-Axl-ADC
UNSPSC
12352100
Target
Antibody-Drug Conjugates (ADCs) ; TAM Receptor
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mecbotamab-vedotin.html
Purity
99.11
Solubility
10 mM in DMSO
Smiles
[Mecbotamabvedotin]
References & Citations
[1]Chang HW, et al. Preclinical development of mecbotamab vedotin (BA3011), a novel, AXL-specific conditional active biologic antibody-drug conjugate. Antib Ther. 2025 Apr 10;8 (2) :145-156.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Scientific Category
Reference compound1
Clinical Information
Phase 2

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