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Mecbotamab

CAT: 0804-HY-P9988-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P9988-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mecbotamab is a humanized IgG1-κ antibody targeting to AXL receptor tyrosine kinase (AXL). Mecbotamab can serves as a conditionally active biologic (CAB), which can be conjugated with MMAE via a cleavable linker, to form ADC Mecbotamab vedotin (BA3011)[2].
CAS Number
2460400-28-4
Product Name Alternative
BA301
UNSPSC
12352203
Target
ADC Antibody; TAM Receptor
Type
Inhibitory Antibodies
Related Pathways
Antibody-drug Conjugate/ADC Related; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mecbotamab.html
Purity
99.9
Solubility
10 mM in DMSO|H2O
Smiles
[Mecbotamab]
Molecular Weight
(145.126 kDa)
References & Citations
[1]Shen G G, et al. Population pharmacokinetic and exposure-response safety analyses of mecbotamab vedotin (BA3011) in patients with advanced solid tumors[J]. 2023.|[2]Mecbotamab. IMGT/mAb-DB.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Isoform
Axl

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