CBX4 Polyclonal Antibody

CAT: 0498-bs-17376R-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0498-bs-17376R-01Size:20 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Synonyms
PC2; NBP16; E3 SUMO-protein ligase CBX4; Chromobox protein homolog 4; Polycomb 2 homolog; hPc2; CBX4
Gene ID
8535
Swiss Prot
O00257
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
401-500/560
Target
CBX4
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human CBX4
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
8535
Predicted Cross Reactivity
Dog, Sheep, Pig, Horse

Related Products

CatalogName
bsm-60681R-01CBX4 Recombinant Antibody
bsm-60681R-TRCBX4 Recombinant Antibody
bs-51080RCBX3 Polyclonal Antibody
bs-53083RCBX2 Polyclonal Antibody
bs-53080RCBX3 Polyclonal Antibody
bs-55037RCBX3 Polyclonal Antibody
bsm-51593MCBX8 Monoclonal Antibody
bsm-62125R-TRCBX2 Recombinant Antibody
bsm-61683R-TRCBX7 Recombinant Antibody
bsm-61683R-01CBX7 Recombinant Antibody

Alternative Products

CatalogName
A-3016-050CBX4 Polyclonal Antibody
TA329637CBX4 Rabbit Polyclonal Antibody
NBP2-92934-0.1mLRabbit Polyclonal CBX4 Antibody
MF-0068820-01Anti-CBX4 Polyclonal Antibody

Popular Products