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PF-06873600

CAT: 0957-S8816-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8816-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-06873600 is an inhibitor of cyclin-dependent kinase 2 (CDK2), CDK4, and CDK6 with Ki values of 0.1, 1.2, and 0.1 nM, respectively, blocks the phosphorylation of retinoblastoma protein (RB1), and limits the proliferation of OVCAR-3 ovarian cancer cells with EC50s of 19 and 45 nM, respectively.
CAS Number
2185857-97-8
Target
CDK
Activity
Cell Cycle
Molecular Formula
C20H27F2N5O4S
Storage Conditions
3 years -20°C powder