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PF-4708671

CAT: 0957-S2163-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S2163-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki/IC50 of 20 nM/160 nM in cell-free assays, 400-fold greater selectivity for S6K1 than S6K2, and 4- and >20-fold selectivity for S6K1 than MSK1 and RSK1/2, respectively. PF-4708671 induces autophagy. First S6K1-specific inhibitor to be reported.
CAS Number
1255517-76-0
Target
S6 Kinase
Activity
MAPK
Molecular Formula
C19H21F3N6
Storage Conditions
2 years -80 in solvent

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