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PF-06840003

CAT: 0957-S8657-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S8657-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-06840003 (EOS200271) is a highly selective orally bioavailable IDO-1 inhibitor. Although it has moderate hIDO1 enzyme inhibition (IC50 0.41 μM), it is a highly efficient compound (LE 0.53, LipE 5.1), driven by its tight packing within the enzyme, as well as the high density of hydrogen bonds it forms with hIDO-1 despite its small size.
CAS Number
198474-05-4
Synonyms
EOS200271
Target
IDO/TDO
Activity
Metabolism
Molecular Formula
C12H9FN2O2
Storage Conditions
2 years -80 in solvent