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BAY 1436032

CAT: 0957-S8530-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0957-S8530-01Size:2 mg
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Description
BAY-1436032 is a highly selective, potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1) . It is a double-digit nanomolar and selective pan-inhibitor of the enzymatic activity of various IDH1-R132X mutants in vitro and displays potent inhibition of 2-HG release (nanomolar range) in patient derived and engineered cell lines expressing different IDH1 mutants.
CAS Number
1803274-65-8
Target
Dehydrogenase
Activity
Metabolism
Molecular Formula
C26H30F3N3O3
Storage Conditions
3 years -20°C powder

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