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BAY 1436032

CAT: 1568-C13472-01Size: 2 mgDry Ice: NoHazardous: No
CAT#: C13472-01Size: 2 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1803274-65-8
SKU
C13472-2mg
Target
Dehydrogenase
Applications
Metabolism
Smiles
CC1CC (CC (C1) (C) C) N2C3=C (C=C (C=C3) CCC (=O) O) N=C2NC4=CC=C (C=C4) OC (F) (F) F
Molecular Formula
C26H30F3N3O3
Additionnal Information
BAY-1436032 is a highly selective, potent and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1) . It is a double-digit nanomolar and selective pan-inhibitor of the enzymatic activity of various IDH1-R132X mutants in vitro and displays potent inhibition of 2-HG release (nanomolar range) in patient derived and engineered cell lines expressing different IDH1 mutants.
Storage Conditions
3 years -20°C powder

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