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VH298

CAT: 0957-S8449-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S8449-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VH298 is a potent VHL (Von Hippel-Lindau, the E3 ligase) inhibitor that stabilizes HIF-α. VH298 blocks the VHL:HIF-α interaction with Kd of 90 nM in isothermal titration calorimetry (ITC) and 80 nM in a competitive fluorescence polarization assay. VH-298 can be used in PROTAC technology.
CAS Number
2097381-85-4
Target
E3 Ligase
Activity
Ubiquitin
Molecular Formula
C27H33N5O4S
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
530908VH298

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