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PIN1 inhibitor API-1

CAT: 0957-S6893-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-S6893-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PIN1 inhibitor API-1 is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor with IC50 of 72.3 nM. PIN1 inhibitor API-1 targets Pin1 peptidyl-prolyl isomerase domain and inhibits Pin1 cis-trans isomerizing activity. PIN1 inhibitor API-1 up-regulates miRNA biogenesis by retaining active XPO5 conformation and suppresses HCC development.
CAS Number
680622-70-2
Target
DNA/RNA Synthesis
Activity
Cell Cycle
Molecular Formula
C15H13F3N6O2
Storage Conditions
3 years -20°C powder

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