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Pidnarulex (CX-5461)

CAT: 0957-S2684-01Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2684-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pidnarulex (CX-5461) is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcription of rRNA with IC50 of 142 nM in HCT-116, A375, and MIA PaCa-2 cells, has no effect on Pol II, and possesses 250- to 300-fold selectivity for inhibition of rRNA transcription versus DNA replication and protein translation.
CAS Number
1138549-36-6
Target
DNA/RNA Synthesis
Activity
Cell Cycle
Molecular Formula
C27H27N7O2S
Storage Conditions
2 years -80 in solvent