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Silmitasertib (CX-4945)

CAT: 0957-S2248-50mgSize: 50 mgDry Ice: YesHazardous: No
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CAT#:0957-S2248-50mgSize:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1009820-21-6
Target
Casein Kinase
Applications
Cell Cycle
Smiles
C1=CC (=CC (=C1) Cl) NC2=NC3=C (C=CC (=C3) C (=O) O) C4=C2C=CN=C4
Molecular Formula
C19H12ClN3O2
Additionnal Information
Silmitasertib (CX-4945) is a potent and selective inhibitor of CK2 (casein kinase 2) with IC50 of 1 nM in a cell-free assay, less potent to Flt3, Pim1 and CDK1 (inactive in cell-based assay) . Silmitasertib induces autophagy and promotes apoptosis. Phase 1/2.
Storage Conditions
2 years -80 in solvent

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