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Allitinib tosylate

CAT: 0957-S2185Size: 5 mgDry Ice: YesHazardous: No
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CAT#:0957-S2185Size:5 mg
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Description
Allitinib tosylate (AST-1306 TsOH, AST-6) is a novel irreversible inhibitor of EGFR and ErbB2 with IC50 of 0.5 nM and 3 nM, also effective in mutation EGFR T790M/L858R, more potent to ErbB2-overexpressing cells, 3000-fold selective for ErbB family than other kinases.
CAS Number
1050500-29-2
Synonyms
AST-1306 TsOH, AST-6
Target
EGFR
Activity
Protein Tyrosine Kinase
Molecular Formula
C24H18ClFN4O2, C7H8O3S
Storage Conditions
2 years -80 in solvent

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