Products for Research Use Only
RegisterLogin

BX-912

CAT: 0957-S1275-01Size: 2 mgDry Ice: YesHazardous: No
Product image 1
1 / 1
CAT#:0957-S1275-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BX912 is a potent and specific PDK1 inhibitor with IC50 of 12 nM, 9- and 105- fold greater selectivity for PDK1 than PKA and PKC in cell-free assays, respectively. In comparison to GSK3β, selectivity for PDK1 is 600-fold.
CAS Number
702674-56-4
Molecular Formula
C20H23BrN8O
Storage Conditions
2 years -80 in solvent

Chemical Information

BX-912

N-[3-[[5-bromo-4-[2-(1H-imidazol-5-yl)ethylamino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide is a member of ureas.

CAS Number702674-56-4
PubChem CID11754511
IUPAC NameN-[3-[[5-bromo-4-[2-(1H-imidazol-5-yl)ethylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide
Molecular FormulaC20H23BrN8O
Molecular Weight471.4
XLogP2.9
Topological Polar Surface Area111
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Heavy Atom Count30
Formal Charge0
Complexity549
SMILES
C1CCN(C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)NCCC4=CN=CN4)Br
InChI
InChI=1S/C20H23BrN8O/c21-17-12-24-19(28-18(17)23-7-6-16-11-22-13-25-16)26-14-4-3-5-15(10-14)27-20(30)29-8-1-2-9-29/h3-5,10-13H,1-2,6-9H2,(H,22,25)(H,27,30)(H2,23,24,26,28)
InChIKey
DMMILYKXNCVKOJ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of BX-912
CAS: 702674-56-4
CID: 11754511
Formula: C20H23BrN8O
MW: 471.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight471.4
XLogP32.9
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass470.11782
Monoisotopic Mass470.11782
Topological Polar Surface Area111 Ų
Heavy Atom Count30
Formal Charge0
Complexity549
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
S1274-10mgBX-795
S1274-25mgBX-795
S1274-100mgBX-795
S1274-01BX-795
S1274-10mM/1mLBX-795
S1274-50mgBX-795
S1274-1gBX-795

Alternative Products

CatalogName
GW1300-1mgBX-912
A11149-25BX-912 25mg
A11149-5BX-912 5mg

Popular Products