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BX-795

CAT: 0957-S1274-01Size: 10 mgDry Ice: YesHazardous: No
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CAT#:0957-S1274-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BX-795 is a potent and specific PDK1 inhibitor with IC50 of 6 nM, 140- and 1600-fold more selective for PDK1 than PKA and PKC in cell-free assays, respectively. Meanwhile, in comparison to GSK3β more than 100-fold selectivity observed for PDK1. BX-795 modulates autophagy via inhibiting ULK1. BX-795 also is a potent TBK1 inhibitor that blocks both TBK1 and IKKε with IC 50 values of 6 nM and 41 nM, respectively.
CAS Number
702675-74-9
Target
IκB/IKK
Activity
NF-κB
Molecular Formula
C23H26IN7O2S
Storage Conditions
2 years -80 in solvent

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