CD133 Polyclonal Antibody, FITC Conjugated

• Background:

  Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

• Synonyms:

  AC133; Antigen AC133; Hematopoietic stem cell antigen; hProminin; PROM1; Prominin I; Prominin like protein 1 precursor; Prominin mouse like 1; prominin1; PROML1; CD133; CORD12; MCDR2; MSTP061; PROML1; RP41; STGD4; PROM1_HUMAN.

• Gene ID:

  8842

• Swiss Prot:

  O43490

• Cellular Locus:

  Cell membrane

• Host:

  Rabbit

• Cross Reactivity:

  Human, Mouse

• Target:

  CD133

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Conjugation:

  FITC

• Source:

  KLH conjugated synthetic peptide derived from human CD133 antigen

• Applications:

  WB, FCM, IF

• Purification:

  Purified by Protein A.

• Excitation Emission:

  494nm/518nm

• Concentration:

  1µg/µl

• Dilution:

  WB (1:300-5000), FCM (1:20-100), IF ()

• Buffer:

  Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

• Modification:

  Unmodified

• Storage Conditions:

  Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

• Gene ID URL:

  8842

• Predicted Cross Reactivity:

  Rat, Fruit Fly