CD133 Polyclonal Antibody

• Background :

  PROM1 encodes a pentaspan transmembrane glycoprotein. Prominin-1 localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

• Description :

  Rabbit Anti-CD133 Polyclonal Antibody

• Product Name Alternative :

  PROM1; Prominin-1; Antigen AC133; Prominin-like protein 1; CD133

• Gene ID :

  8842

• Accession Number :

  O43490

• Reactivity :

  Human, Mouse

• Immunogen :

  Synthesized peptide derived from the N-terminal region of human CD133

• Clonality :

  Polyclonal

• Tag :

  Prominin-1

• Applications :

  WB, IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  100kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  CD133 Polyclonal Antibody detects endogenous levels of CD133 protein.

• Observed Molecular Weight :

  100

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:100-300; Not yet tested in other applications.

• Other Product Names :

  PROM1; Prominin-1; Antigen AC133; Prominin-like protein 1; CD133

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/O43490

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG