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JNJ-10198409

CAT: 0957-E2393Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0957-E2393Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ-10198409, a relatively selective, orally active, and ATP competitive PDGF-RTK (platelet-derived growth factor receptor tyrosine kinase) inhibitor with IC50 of 2 nM, is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent, has good activity against PDGFRβ kinase and PDGFRα kinase with IC50 of 4.2 and 45 nM, respectively.
CAS Number
627518-40-5
Target
PDGFR
Activity
Protein Tyrosine Kinase
Molecular Formula
C18H16FN3O2
Storage Conditions
3 years -20°C powder