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JNJ-?10198409

CAT: 0013-GTR19155126-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19155126-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM) . JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM) . It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.
CAS Number
627518-40-5
Purity
>98% (HPLC)
Solubility
DMSO:83.33 mg/mL (256.13 mM; Need ultrasonic)
Smiles
COC1=C (C=C2C (=C1) CC3=C2NN=C3NC4=CC (=CC=C4) F) OC
Molecular Formula
C18H16FN3O2
Molecular Weight
325.34
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.

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