JNJ-10198409

• Target:

  PDGFR

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity:

  0.9851

• Bioactivity:

  JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM) . JNJ-10198409 has good activity against PDGFR-? kinase (IC50=4.2 nM) and PDGFR-? kinase (IC50=45 nM) . It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.

• Smiles:

  COc1cc2Cc3c(Nc4cccc(F)c4)n[nH]c3-c2cc1OC

• Molecular Formula:

  C18H16FN3O2

• Molecular Weight:

  325.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  627518-40-5