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JNJ-10198409

CAT: 0931-T15616-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15616-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
627518-40-5
Target
PDGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Purity
0.9851
Bioactivity
JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM) . JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM) . It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.
Smiles
COc1cc2Cc3c(Nc4cccc(F)c4)n[nH]c3-c2cc1OC
Molecular Formula
C18H16FN3O2
Molecular Weight
325.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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