JNJ-10198409

• Target :

  PDGFR

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity :

  0.9851

• Bioactivity :

  JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM) . JNJ-10198409 has good activity against PDGFR-? kinase (IC50=4.2 nM) and PDGFR-? kinase (IC50=45 nM) . It is a dual-mechanism, antiangiogenic, and tumor cell antiproliferative agent.

• Smiles :

  COc1cc2Cc3c(Nc4cccc(F)c4)n[nH]c3-c2cc1OC

• Molecular Formula :

  C18H16FN3O2

• Molecular Weight :

  325.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  627518-40-5