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Phlorizin

CAT: 0957-S2343-02Size: 1 gDry Ice: YesHazardous: No
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CAT#:0957-S2343-02Size:1 g
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Description
Phlorizin (Phloridzin) is a dihydrochalcone found in the bark of pear (Pyrus communis), apple, cherry and other fruit trees. Phlorizin is a non-selective SGLT inhibitor with Ki of 300 nM and 39 nM for hSGLT1 and hSGLT2, respectively. Phlorizin is also a Na+/K+-ATPase inhibitor.
CAS Number
60-81-1
Synonyms
Phloridzin
Target
SGLT
Activity
GPCR & G Protein
Molecular Formula
C21H24O10
Storage Conditions
2 years -80 in solvent

Chemical Information

Phloridzin

phloridzin has been reported in Malus, Lithocarpus litseifolius, and other organisms with data available.

CAS Number60-81-1
PubChem CID45933907
IUPAC Name1-[2,4-dihydroxy-6-[(2S,4R,5S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one
Molecular FormulaC21H24O10
Molecular Weight436.4
XLogP1.2
Topological Polar Surface Area177
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Heavy Atom Count31
Formal Charge0
Complexity581
SMILES
C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O[C@H]3C([C@@H]([C@@H](C(O3)CO)O)O)O)O)O)O
InChI
InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16?,18-,19-,20?,21-/m1/s1
InChIKey
IOUVKUPGCMBWBT-HXBJIUPGSA-N
Chemical Structure
2D Structure
2D structure of Phloridzin
CAS: 60-81-1
CID: 45933907
Formula: C21H24O10
MW: 436.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight436.4
XLogP31.2
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Exact Mass436.13694696
Monoisotopic Mass436.13694696
Topological Polar Surface Area177 Ų
Heavy Atom Count31
Formal Charge0
Complexity581
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
HY-N0143-01Phlorizin
T2S2003-01Phlorizin dihydrate
HY-N0143A-01Phlorizin (dihydrate)
E1KS2343Phlorizin (Phloridzin)
JH303566Phlorizin chalcone
A10724-5000Phlorizin 5g
A10724-1000Phlorizin 1g
A10724-500Phlorizin 500mg

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