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Idasanutlin

CAT: 0498-bs-83758C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-83758C-01Size:5 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Idasanutlin is a potent (IC50 = 6 nM) and selective inhibitor of MDM2, the primary negative regulator of p53.1 It blocks the p53-MDM2 interaction activating the p53 pathway leading to cell cycle arrest and apoptosis. Idasanutlin has displayed efficacy in the treatment of multiple cancers alone and in combination with other chemotherapeutics.2-6
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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