Products for Research Use Only

GW3965 HCl

CAT: 0498-bs-83713C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-83713C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GW3965 is a potent and selective LXR agonist, activating human LXRα and β in cell-based reporter gene assays (EC50=190 and 30 nM respectively) .1 Since LXR is a master regulator of cholesterol and fatty acid metabolism, GW3965 exerts a variety of effects including antiatherosclerotic2, antiinflammatory3 as well as antinociceptive4 and alteration of fat tissue distribution5. Orally active.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C