Products for Research Use Only
RegisterLogin

Tepotinib

CAT: 0498-bs-83435C-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0498-bs-83435C-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Tepotinib is a selective type 1b MET inhibitor. In biochemical assays using His6-tagged recombinant human MET kinase domain, tepotinib inhibited kinase activity in a concentration-dependent manner with IC50=1.8 nM.1 It displays marked antitumor activity in MET-dependent tumor models.2 It crosses the blood-brain barrier and displays intracranial antitumor activity.3 Tepotinib can overcome EGFR inhibitor resistance mediated by aberrant c-Met activation4 and is in clinical use for non-small cell lung cancer harboring MET exon 14 skipping alterations.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

Alternative Products

CatalogName
T6121-01Tepotinib
HY-14721ATepotinib (hydrochloride)
HY-14721R-01Tepotinib (Standard)
RM-T283007-01Tepotinib Impurity 7
RM-T283006-01Tepotinib Impurity 6
RM-T283003-01Tepotinib Impurity 3
RM-T283002-01Tepotinib Impurity 2
RM-T283005-01Tepotinib Impurity 5
RM-T283004-01Tepotinib Impurity 4
T9601-01Tepotinib hydrochloride (1 : x)

Popular Products