Topotecan (acetate)

• Description:

  Topotecan acetate is a topoisomerase inhibitor.

• Product Name Alternative:

  SKF 104864A (acetate) ; NSC 609669 (acetate)

• UNSPSC:

  12352005

• Target:

  Topoisomerase

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C1[C@] (O) (CC) C2=C (CO1) C (N3CC4=CC5=C (CN (C) C) C (O) =CC=C5N=C4C3=C2) =O.CC (O) =O

• Molecular Formula:

  C25H27N3O7

• Molecular Weight:

  481.50

• References & Citations:

  [1]Kollmannsberger C, et al. Topotecan - A novel topoisomerase I inhibitor: pharmacology and clinical experience. Oncology. 1999;56 (1) :1-12.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 4

• CAS Number:

  123948-88-9