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ODQ

CAT: 498-bs-83167C-01Size: 5 mgDry Ice: NoHazardous: No
5 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A potent and selective inhibitor of soluble guanylyl cyclase (sGC), IC50 = 20 nM) .1 ODQ acts via competition with NO for the heme site of sGC where it binds irreversibly.2 ODQ does not inhibit NO-mediated macrophage toxicity, an activity that is unrelated to cGMP nor does it inhibit particulate GC.1 ODQ is an extremely useful tool to explore the involvement of the NO-cGMP pathway in cellular signaling and physiologic processes.3-5
Conjugation
Unconjugated
Buffer
Pale-yellow solid
Storage Conditions
-20°C

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