ODQ (Standard)

• Description :

  ODQ (Standard) is the analytical standard of ODQ. This product is intended for research and analytical applications. ODQ is a potent and selective soluble guanylyl cyclase (sGC, nitric oxide-activated enzyme) inhibitor. ODQ enhances the pro-apoptotic effects of Cisplatin in human mesothelioma cells[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Guanylate Cyclase; Reference Standards

• Related Pathways :

  Apoptosis; GPCR/G Protein; Others

• Field of Research :

  Cancer

• Smiles :

  O=C1ON=C2N1C3=C(C=CC=C3)N=C2

• Molecular Formula :

  C9H5N3O2

• Molecular Weight :

  187.16

• References & Citations :

  [1]Ronald Fiscus, et al. ODQ, an inhibitor of soluble guanylyl cyclase (nitric oxide-activated enzyme), enhances the pro-apoptotic effects of cisplatin in human mesothelioma cells. Cancer Res May 1 2007 (67) (9 Supplement) LB-43.|[2]Zacharowski K, et al. The selective guanylate cyclase inhibitor ODQ reduces multiple organ injury in rodent models of Gram-positive and Gram-negative shock. Crit Care Med. 2001;29 (8) :1599-1608.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [41443-28-1]