Necrostatin-1

CAT: 0498-bs-83160C-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0498-bs-83160C-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Necrostatin-1 is an inhibitor of necroptosis (non-apoptotic cell death pathway; EC50 = 494 nM) .1 It is an ATP-competitive death domain receptor-associated adaptor kinase (RIP1) inhibitor (EC50 = 182 nM) .2 It displays a protective effect in a mouse model of ischemic brain injury1, inhibits myocardial cell death and reduces infarct size in various mouse heart models3 and inhibits glutamate-induced oxytosis in HT-22 cells4.

Conjugation

Unconjugated

Buffer

Pale yellow solid

Storage Conditions

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HY-15760-01	Necrostatin-1

Necrostatin-1

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