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AZ20

CAT: 0498-bs-82981C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82981C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
AZ20 is a potent and highly selective inhibitor of Ataxia telangiectasia mutated and RAD3-related (ATR) kinase (IC50 = 5 nM in vitro; IC50 = 50 nM in HT29 colorectal adenocarcinoma cells) .1 Combination therapy with AZ20 and gemcitabine resulted in synergistic inhibition of tumor cell growth and cell death initiation in pancreatic cancer cell lines.2
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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