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AZ20

CAT: 1410-M10924-07Size: 100 mgDry Ice: NoHazardous: No
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CAT#:1410-M10924-07Size:100 mg
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Description
AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay, 8-fold selectivity over mTOR.
CAS Number
1233339-22-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
412.51
Molecular Formula
C21H24N4O3S
Notes
Research use only, not for human use.
Receptor
ATR| mTOR

Chemical Information

(3R)-4-(2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl)-3-methylmorpholine

(3R)-4-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)-4-pyrimidinyl]-3-methylmorpholine is a member of indoles.

CAS Number1233339-22-4
PubChem CID46244454
IUPAC Name(3R)-4-[2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl]-3-methylmorpholine
Molecular FormulaC21H24N4O3S
Molecular Weight412.5
XLogP2.1
Topological Polar Surface Area96.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count29
Formal Charge0
Complexity707
SMILES
C[C@@H]1COCCN1C2=NC(=NC(=C2)C3(CC3)S(=O)(=O)C)C4=C5C=CNC5=CC=C4
InChI
InChI=1S/C21H24N4O3S/c1-14-13-28-11-10-25(14)19-12-18(21(7-8-21)29(2,26)27)23-20(24-19)16-4-3-5-17-15(16)6-9-22-17/h3-6,9,12,14,22H,7-8,10-11,13H2,1-2H3/t14-/m1/s1
InChIKey
SCGCBAAYLFTIJU-CQSZACIVSA-N
Chemical Structure
2D Structure
2D structure of (3R)-4-(2-(1H-indol-4-yl)-6-(1-methylsulfonylcyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
CAS: 1233339-22-4
CID: 46244454
Formula: C21H24N4O3S
MW: 412.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight412.5
XLogP32.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass412.15691181
Monoisotopic Mass412.15691181
Topological Polar Surface Area96.6 Ų
Heavy Atom Count29
Formal Charge0
Complexity707
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
A3210-5AZ20

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