PF-9366

CAT: 0498-bs-82960C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82960C-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM) .1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50’s of 1.2 µM and 225 nM respectively.
Conjugation
Unconjugated
Buffer
Beige solid
Storage Conditions
-20°C

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