SRT1720 HCl

CAT: 0498-bs-82956C-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0498-bs-82956C-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

SIRT1 activator (EC1.5 = 0.16 µM, max activation = 781%) .1 It reduced glucose levels and hyperinsulinemia in DIO, Lepob/ob mice and Zucker fa/fa rats. SRT1720 enhanced endurance running and protected against diet-induced obesity and insulin resistance via enhancement of oxidative metabolism in skeletal muscle, liver, and brown adipose tissue.2 It induced mitochondrial biogenesis in oxidant-induced renal proximal tube cell injury.3 SRT1720 repressed circadian clock gene expression and decreased H3 K9/K14 acetylation in a time-specific manner.4 It attenuated angiotensin II-induced atherosclerosis by inhibiting the vascular inflammatory response.5

Conjugation

Unconjugated

Buffer

White solid

Storage Conditions

-20°C

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Catalog	Name
MBS3600020-01	SRT1720
A4180-100	SRT1720 HCl
FP71690-01	SRT1720 hydrochloride
A10862-10	SRT1720 10mg
A10862-200	SRT1720 200mg

SRT1720 HCl

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