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BD1063 dihydrochloride

CAT: 0498-bs-82826C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82826C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BD1063 is potent and selective sigma-1 antagonist (IC50’s: sigma1 = 9nM, sigma2 = 449nM) .1 BD1063 abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a sigma1 dependent manner.2 BD1063 potentiated µ-opioid antinociception in mice in a sigma-dependent manner.3 BD-1063 has been used in animal models to successfully treat compulsive eating4 and excessive ethanol drinking5.
Conjugation
Unconjugated
Buffer
Off-white solid
Storage Conditions
-20°C

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