MPEP HCl

CAT: 0498-bs-82751C-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0498-bs-82751C-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

MPEP is a potent (IC50 = 36 nM for quisqualate-stimulated phosphoinositide hydrolysis) and selective (over mGlu1b, -2, -3, -4a, -6, -7b, and -8a) antagonist of the metabotropic glutamate receptor subtype 5 (mGlu5) .1 It is a positive allosteric modulator of human mGlu4.2 MPEP inhibition of mGlu5 has been studied for the treatment of many CNS disorders including Parkinson’s3,4, Fragile X syndrome5, and addiction6.

Conjugation

Unconjugated

Buffer

White or pale yellow solid

Storage Conditions

-20°C

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Alternative Products

Catalog	Name
B1628-10	MPEP
HY-14609-01	MPEP (Hydrochloride)
456629-01	MPEP Hydrochloride
abx282936-01	MPEP HCl

MPEP HCl

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