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Flavopiridol HCl

CAT: 0498-bs-82641C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82641C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cyclin-dependent kinase (CDK) inhibitor that causes cell cycle arrest at G1 and G2 phase1. Potentiates (100-200 nM) PMA-induced apoptosis in HL-60 and U937 cells2. Potentiates the effects of topoisomerase I inhibitors by suppressing Rad51 expression in a p53-dependent manner. Displays potent antiviral activity against HIV-1 and HSV-1 in vitro4.
Conjugation
Unconjugated
Buffer
Light yellow solid
Storage Conditions
-20°C

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