KT-5823

• Background:

  Selective protein kinase G inhibitor (Ki =0.23, 4 and >10 μM for PKG, PKC and PKA respectively1. Arrests human skin fibroblast cell cycle after the G0/G1 boundary2. Abolishes the cGMP-induced relaxation in smooth muscle cells (IC50=60 nM) 3. Cell permeable.

• Conjugation:

  Unconjugated

• Buffer:

  White or off-white solid

• Storage Conditions:

  -20°C