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NSC95397

CAT: 0498-bs-82323C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82323C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A potent and selective inhibitor of Cdc25 phosphatase (Ki = 32, 96 and 40 nM for Cdc25A, B and C respectively) . NSC-95397 inhibits the growth of several human tumor cell lines and blocks G2/M cell cycle transition.1 Induces cell cycle arrest, phosphorylation of EGFR and activation of ERK-1 and -2.2 Inhibits carboxyl-terminal binding protein a transcriptional corepressor that suppresses multiple pro-apoptotic and epithelial genes.3 Induces eryptosis in human erythrocytes.4
Conjugation
Unconjugated
Buffer
Orange solid
Storage Conditions
-20°C

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CatalogName
C12200-25mgNSC95397

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