NSC95397

CAT: 0957-S6777-5mgSize: 5 mgDry Ice: NoHazardous: No
CAT#:0957-S6777-5mgSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
93718-83-3
Target
CDK
Applications
Cell Cycle
Smiles
C1=CC=C2C (=C1) C (=O) C (=C (C2=O) SCCO) SCCO
Molecular Formula
C14H14O4S2
Additionnal Information
NSC 95397 is a potent, selective Cdc25 dual specificity phosphatase inhibitor with Ki of 32 nM, 96 nM, 40 nM for Cdc25A, Cdc25B and Cdc25C, respectively. NSC 95397 has IC50 of 22.3 nM, 56.9 nM and 125 nM for human Cdc25A, human Cdc25C and Cdc25B, respectively. NSC 95397 inhibits mitogen-activated protein kinase phosphatase-1 (MKP-1) and suppresses proliferation and induces apoptosis in colon cancer cells through MKP-1 and ERK1/2 pathway.
Storage Conditions
3 years -20°C powder

Alternative Products

CatalogName
MBS133400NSC95397

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