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UCF-101

CAT: 0498-bs-82315C-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0498-bs-82315C-01Size:5 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
UCF-101 is a potent, specific, competitive, and reversible inhibitor of the pro-apoptotic, mitochondrial serine protease Omi/HtrA2 (IC50 = 9.5 μM for His-Omi134-458) . Shows very little activity against various other serine proteases tested (IC50 ≥ 200 μM) .1 Mitigates streptozotocin-induced cardiomyocyte dysfunction.2 Protects against cerebral oxidative injury and cognitive impairment in a rat model.3 Cell permeable.
Conjugation
Unconjugated
Buffer
Orange solid
Storage Conditions
-20°C

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