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CUDC-101

CAT: 0498-bs-82507C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82507C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A novel hybrid dual-acting HDAC and receptor tyrosine kinase inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2, IC50 = 4.4, 2.4 and 15.7 nM respectively.1 It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors.1,2
Conjugation
Unconjugated
Buffer
White or off-white solid
Storage Conditions
-20°C

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