Anagrelide HCl

• Background:

  Potent and selective phosphodiesterase (PDE3) inhibitor, IC50=36 nM) .1 Inhibits platelet production by disrupting megakaryocyte maturation2 via a mechanism which is independent of PDE3 inhibition3. Clinically useful agent for conditions requiring platelet lowering therapy.4,5

• Conjugation:

  Unconjugated

• Buffer:

  White solid

• Storage Conditions:

  -20°C