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GSK-1016790A

CAT: 0498-bs-82129C-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0498-bs-82129C-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
A novel and potent TRPV4 channel agonist. GSK1016790A induced Ca2+ influx in mouse and human TRPV4 expressing HEK cells (EC50 values of 18 and 2.1 nM, respectively), and evoked a dose-dependent activation of TRPV4 whole-cell currents at concentrations above 1 nM. It is 300-fold more potent than 4α-PDD and is a valuable tool for investigating the role of TRPV4 in physiological processes.
Conjugation
Unconjugated
Buffer
White solid
Storage Conditions
-20°C

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