Anti-HERV Antibody

• Background:

  HERVs are a class of multiple sclerosis associated retroviruses. Reacts with a replication competent Human Endogenous Retrovirus (HERVW) isolated from placenta. The synthetic peptide sequence used as immunogen is taken from the virus envelope polyprotein sequence. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. The HERVW endogenous envelope protein has retained its original fusogenic properties and participates in trophoblast fusion during placenta morphogenesis.

• Description:

  Our HERV rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human endogenous retrovirus (HERV) and is antigen affinity purified. It is great for use in WB.

• Synonyms:

  Human Endogenous Retrovirus, HERVW

• Other Statements:

  For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

• Host:

  Rabbit

• Reactivity:

  Human Endogenous Retrovirus (HERV)

• Immunogen:

  Synthetic peptide corresponding to amino acids from human Endogenous Retrovirus (HERV)

• Immunogen Type:

  Human Endogenous Retrovirus

• Target:

  HERV

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Applications:

  WB

• Format:

  Antigen Affinity Purified

• Form:

  Liquid

• Buffer:

  PBS + 0.02% NaN3

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

• WB Dilution:

  1:500-1:1000

• Specificity:

  Reacts with a replication-competent human Endogenous Retrovirus (HERV) isolated from placenta. HERVs are a class of multiple-sclerosis-associated retroviruses.

• Formulation:

  Prepared from pooled rabbit serum by affinity purification using a column to which the peptide immunogen was coupled.

• Quality Control:

  Western blots performed on each lot.

• Isotype:

  IgG