HERV Antibody

CAT: 0223-61-446Size: 200 µLDry Ice: NoHazardous: No
CAT#:0223-61-446Size:200 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
NCBI Gene ID
30816
Swiss Prot
Q9UQF0
Accession Number
Q9UQF0
Host
Rabbit
Reactivity
Human
Immunogen
This HERV (ERVWE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-429 amino acids from the Central region of human HERV (ERVWE1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
60 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ERVW-1
NCBI Official Name
Syncytin-1
NCBI Organism
Homo sapiens
Background Reference 01
Oluwole, S.O., Amyotroph Lateral Scler (2), 67-72 (2007)
Background Reference 02
Gong, R., Cell. Physiol. Biochem. 20 (5), 517-526 (2007)
Background Reference 03
Antony, J.M., AIDS Res. Hum. Retroviruses 22 (12), 1253-1259 (2006)
Other Product Names
Syncytin-1, Endogenous retrovirus group W member 1, Env-W, Envelope polyprotein gPr73, Enverin, HERV-7q Envelope protein, HERV-W envelope protein, HERV-W_7q212 provirus ancestral Env polyprotein, Syncytin, Surface protein, SU, gp50, Transmembrane protein, TM, gp24, ERVW-1, ERVWE1
Tested Applications
WB
Protein ID
47605755
Physical Properties
Liquid

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