Recombinant Human Vitronectin

• Background:

  Vitronectin is a multifunctional glycoprotein present in blood and in the extracellular matrix. It binds glycosaminoglycans, collagen, plasminogen and the urokinase-receptor, and also stabilizes the inhibitory conformation of plasminogen activation inhibitor-1. Vitronectin may play an important role in wound healing and in tumorprogression. Vitronectin deposition has been detected in areas of brosis and necrosis in a variety of diseases, including membranous nephropathy, arteriosclerosis and degenerative central nervous system disorders.

• Product Name Alternative:

  Vitronectin; VTN; VN; V75; Serum-spreading factor

• Accession Number:

  AAH05046.1

• Host:

  E.coli

• Endotoxin:

  <0.01 EU/µg as determined by LAL test.

• Purity:

  Greater than 95% as determined by reducing SDS-PAGE

• Form:

  Liquid

• Reconstitution:

  0

• Molecular Weight:

  47.6 KDa

• Shipping Conditions:

  The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

• Storage Conditions:

  Store at -70°C/-20°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

• Formulation:

  Supplied as a 20mM PB, 10%Trehalose, 0.02%Tween80, pH 7.8.

• Construct:

  Recombinant Human Vitronectin is produced by our E.coli expression system and the target gene encoding Val62-Leu478 is expressed.

• Species:

  Human