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BFC1108

CAT: 0804-HY-161276-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161276-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BFC1108 is a small molecule Bcl-2 functional converter. BFC1108 induces a conformational change in Bcl-2, resulting in the exposure of its BH3 domain both in vitro and in vivo. BFC1108 effectively induces apoptosis in Bcl-2 expressing cancers.[1].
CAS Number
692774-37-1
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bfc1108.html
Concentration
10mM
Purity
98.11
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCOC1=CC=CC=C1NC(C2=CC(Cl)=CC=C2NC(C3=CC=C(OC)C=C3)=O)=O
Molecular Formula
C23H21ClN2O4
Molecular Weight
424.88
References & Citations
[1]Kopparapu PR, et al. Identification and characterization of a small molecule Bcl-2 Functional Converter. Cancer Res Commun. 2024 Feb 8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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