KD 5170

• Description :

  KD 5170 is a pan inhibitor of histone deacetylases (HDACs) and exhibits broad spectrum antitumor activity in vitro and in vivo[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  HDAC

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/kd-5170.html

• Purity :

  98.13

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=S(NC1=CC=C(C(CSC(C)=O)=O)C=N1)(C2=CC=C(OCCCN(C)C)C=C2)=O

• Molecular Formula :

  C20H25N3O5S2

• Molecular Weight :

  451.56

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Hassig CA, et al. KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo. Mol Cancer Ther. 2008 May;7 (5) :1054-65.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [940943-37-3]