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SIRP alpha Antibody

CAT: 0667-KC-1075-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-1075-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1, Signal-regulatory protein alpha-2, Sirp-alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-3, p84, CD antigen CD172a
Gene Name
SIRPA
Gene ID
140885
UniProt
P78324
Antigen Species
Human
Reactivity
Human
Cross Reactivity
Not tested
Immunogen
Recombinant human SIRPA
Target Antigen
CD172a
Target
PP-817
Partner Proteins
Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; Signal-regulatory protein alpha-2; Sirp-alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-3; p84; CD antigen CD172a
Clone
K06318_28G4
Conjugation
Unconjugated
Applications
Top_IHC&Top_IP/ChIP&Top_WB
Validation
Top_IHC&Top_IP/ChIP&Top_WB
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 81%, Pig - 85%, Cynomolgus monkey - 98%
Purity
≥85%
Cores
AQGSTSSTRLHEPEKNAREITQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKPEPSFSEYASVQ
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
79%
Recombinant Antibody
Not recombinant
IHC Dilution
1:200
WB Dilution
1:1000
IP Dilution
1:100
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP
Target Alternative Name
SIRP alpha
Panel Description
CD Antigen
Host or Source
Mouse
Protein Name
Signal regulatory protein alpha
WB Description
Succeed
IHC description
Succeed
IP description
Succeed
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG1

UniProtKB · P78324

Tyrosine-protein phosphatase non-receptor type substrate 1

SHPS1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P78324
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SIRPA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
SHP substrate 1, SHPS-1
EC number
—
Processing
Precursor
Secondary accessions
A2A2E1, A8K411, B2R6C3, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainRepeatSH3-bindingSignalTransmembraneTransmembrane helix

Cellular component

Membrane

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